One example of a logical signal transduction pathway is the activation of the cAMP (cyclic adenosine monophosphate) pathway. This pathway is commonly used in response to extracellular signals such as hormones or neurotransmitters.
The pathway begins with the binding of a ligand (e.g., hormone) to a cell surface receptor. This receptor then activates a G protein, which in turn activates an enzyme called adenylyl cyclase. Adenylyl cyclase converts ATP (adenosine triphosphate) into cAMP.
cAMP acts as a second messenger and can diffuse throughout the cell, activating protein kinase A (PKA). PKA then phosphorylates target proteins, leading to various cellular responses.
Overall, this pathway allows for the amplification and integration of extracellular signals, enabling the cell to respond appropriately to its environment.
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