You might also be interested to know that researchers have just calculated the average age of human liver cells and found that regardless of age The liver is only about three years old!
Ability to rebuild the liver and ask questions about it!
It is interesting to know that the liver can regenerate itself after injury! But whether this ability disappears with age has long been unknown. Until a new study shows that aging does not slow down the liver regeneration process, and whether you are 20 or 80 years old, the liver is on average three years old in your lifetime.
The liver has a high risk of detoxifying the body and is regularly exposed to toxins, the risk of further damage to this organ is always higher than other organs. For this reason, the liver has a remarkable ability to regenerate throughout life, which is unique among the organs of the body. Aging This ability to weaken or slow down, remained a mystery. Even a study of animal specimens did not clarify this! Thus, such questions became a new impetus for further study by TU Dresden researchers.
What is the relationship between the
atomic bomb and the measurement of cell age? Olaf
Bergmann, who led the study, acknowledged that some studies have
suggested that liver cells may have a long lifespan, while others
show a steady return. Bergman emphasizes that if we want to know
exactly What happens in the human body, we must find a way
to directly assess the age of liver cells.
To find a solution, Bergman's research team turned to a strange source, and this source The strange thing was the nuclear tests of the 1950s. When nuclear bombs explode above the ground, huge amounts of radioactive carbon enter the Earth's atmosphere and subsequently enter the DNA of plants and animals. In general, after the ban on nuclear experiments in 1963, the level of radioactive carbon in the Earth's atmosphere decreased year by year, and this decrease included the amount of radioactive carbon in the cells of living organisms.
Although this amount of radioactive carbon is small (it is not harmful!) In the body of organisms, they can be identified and measured in tissue samples. By comparing the amount of radioactive carbon in the body with the amount in the atmosphere, we can look back and determine the age of the cells.
To put this idea into practice, researchers measured the level of radioactive carbon in the liver. Thirty-three deaths ranging from 20 to 84 years old were analyzed. An interesting finding in this study was that the livers of all of these individuals were almost homogeneous; In fact, the average age of the liver was a little less than three years (regardless of age)!The liver of all people who died between the ages of 20 and 84 was almost the same! In fact, their average liver age was slightly less than three years (regardless of age). Of course, it should be noted that not all cells in a given liver are the same age, and some are regenerated each year (or more each year), while others can survive for up to a decade. On the other hand, it is interesting that longer-lived hepatocytes contain more sets of chromosomes.
The human liver is made up of cells with different amounts of DNA. In general, most cells (shown with a white arrow!) Have two copies of DNA. While some cells collect more sets of DNA (shown with yellow arrows!). Therefore, different types of cells in the liver are regenerated and regenerated differently.
Finally, it should be noted that the process of cell regeneration and renewal in the liver can serve as a protective mechanism. Consider that it protects us from the accumulation of harmful mutations. It should be noted that this research has been published in more detail in the journal "Cell Systems". ul>
Source: NEW ATLAS