The invention of smart eye lenses that easily detect cancer

In their latest studies, researchers have been able to invent smart eye lenses that have the ability to detect cancer in the early stages of the disease. Cancer detection is done by finding certain chemicals in tears. This invention has made a lot of noise in the field of cancer treatment.

BingMag.com The invention of smart eye lenses that easily detect cancer

In their latest studies, researchers have been able to invent smart eye lenses that have the ability to detect cancer in the early stages of the disease. Cancer detection is done by finding certain chemicals in tears. This invention has made a lot of noise in the field of cancer treatment.

The first and most important feature of the smart lenses that have been made is the cheapness of the device. The patient can have a lens test for a reasonable fee. Scientists can also optimize the lenses so that this object is able to detect not one disease, but several disease models. However, the question may arise, what exactly is the mechanism of lenses and how can human tears show various diseases?

To explain the mechanism of smart lenses, we need to look at exosomes. ) Cited. Exosomes can influence tumor regulation, growth and spread. For this reason, for several years, scientists have shown interest in exploiting exosomes, separately and also in combination with other materials such as nanoparticles. Very briefly, exosomes can be considered a model of bubble-like messengers that contain cells that are secreted in blood, saliva, urine, and tears. In other words, exosomes are vesicles carrying nucleic acids, proteins, lipids and metabolites that are used as an interface between healthy and diseased cells.

BingMag.com The invention of smart eye lenses that easily detect cancer

Certainly, identifying cancer at the very beginning of the disease's progression can increase the survival rate and, consequently, the quality of life of patients. Normally, every month that cancer progresses in the patient's body, the risk of dying from cancer increases by 10%. Professor Ali Khadem Al-Hosseini, as the head of this project at the Tarasaki Institute in the United States of America, says this about these smart lenses:

These lenses are able to detect exosomes in different solutions from various cell lines and human tears. to identify The lenses can detect the expression of cell surface proteins known as cancer biomarkers. The lens glass has tiny chambers that bind to the antibodies; Antibodies that bind to exosomes themselves.

In the pilot project of Dr. Khadim al-Hosseini, lenses have been tested on exosomes secreted from 10 different types of tissues and cancer cell lines. Also, 10 volunteers were used for this purpose in terms of checking and correctness of lens operation in humans. Khadim al-Husseini explains:

The lenses can be stained with specific antibodies that bind to nanoparticles so that the lenses have the power to detect a specific biomarker. Based on this, lenses can be used for cancer screening; Because it is a very easy, fast, highly sensitive, non-invasive and affordable tool. Exosomes are a very rich source of markers that can be used for many medical applications. The method and method of our team has been able to achieve important achievements for this purpose. The field of exosomes has been developed so that certain devices can be used as a good diagnostic agent in the clinic. However, several challenges are facing the researchers. In the method used by Tarasaki company, lenses are made that are affordable and, on the other hand, the difficult, complicated and time-consuming process to detect cancer is not used. Another important point lies in the fact that tears are a much better source for exosomes; Because tears are cleaner and are considered a more reliable source than other body fluids.

For the production and engineering of housings and lenses, direct laser cutting technique was used instead of the usual cast molding method. Also, chemically, the surface of the lens is worked on so that the surface of the lens has the necessary preparation for antibody binding. In fact, these are the antibodies on the surface of the lens that are attached to the exosomes and check the signs of cancer.

Dr. Khadim al-Hosseini, while considering this invention as "encouraging", adds to his words at the end that smart contact lenses It is a very suitable and promising platform for cancer detection, which benefits from three favorable features: ease of use, speed of detection, and non-invasiveness of the approach to cancer detection.

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