What is drug interaction and which drugs and foods should not be taken together?

Today we live in a world where there are many treatment options to control various diseases. However, the increased availability of drugs has increased the possibility of drug interactions. Drug interactions mean that the simultaneous use of a drug with other drugs, foods, drinks or herbs can change its effect in the body. In other words, make the drug more or less effective than expected or lead to unexpected side effects. To learn about the most important drug interactions, read this article from BingMag until the end.

BingMag.com What is drug interaction and which drugs and foods should not be taken together?

Today we live in a world where there are many treatment options to control various diseases. However, the increased availability of drugs has increased the possibility of drug interactions. Drug interactions mean that the simultaneous use of a drug with other drugs, foods, drinks or herbs can change its effect in the body. In other words, make the drug more or less effective than expected or lead to unexpected side effects. To learn about the most important drug interactions, read this article from BingMag until the end.

Types of drug interactions

There are different types of drug interactions that you should be aware of. Let's examine each of these interactions together.

Drug-Drug Interaction

A drug-drug reaction occurs when two or more different drugs interact. For example, the simultaneous use of the anticoagulant drug Warfarin and the antifungal drug Fluconazole increases the risk of bleeding. An over-the-counter drug or an over-the-counter drug is created with a drug prescribed by a doctor. Herbs and dietary supplements are some of the most common over-the-counter medications.

An example of this interaction can occur between a diuretic (a drug that rids the body of excess water and salt) and ibuprofen. Ibuprofen may reduce the effectiveness of diuretics because it causes water and salt retention in the body. jpg">

This reaction occurs when the consumption of a certain food or drink changes the effect of the drug. For example, some statins used to treat high cholesterol interact with grapefruit juice. If you use these statins, drinking grapefruit juice may cause the drug to remain in the body and increase the risk of liver damage or kidney failure.

Other consequences of statin and grapefruit juice interactions include rhabdomyolysis. . This complication occurs when a protein called myoglobin is released into the blood due to the breakdown of skeletal muscle, which can damage the kidneys. With alcohol, they cause fatigue and delayed reaction. They can also increase the risk of negative side effects. For example, simultaneous consumption of alcohol or drugs containing alcohol with the antibiotic metronidazole (Metronidazole) causes flushing, vomiting and abdominal pain.

Drug-disease interaction

This interaction occurs when The use of medicine changes or worsens a disease. In addition, certain medical conditions can increase the risk of side effects from medications.

For example, a number of decongestants used to treat the common cold raise blood pressure and are suitable for people with high blood pressure. are not. Another example is metformin (diabetes medicine) and kidney disease. People with kidney disease should use a lower dose of metformin or not take it at all. Because metformin can accumulate in the kidneys of these patients and increase the risk of severe side effects. they let. For example, tricyclic antidepressants interfere with skin tests used to determine allergies.

Most Important Drug Interactions

BingMag.com What is drug interaction and which drugs and foods should not be taken together?

In this section, we will introduce the most important substances that can change the effectiveness of drugs.

Grapefruit

As mentioned, consuming grapefruit with Some drugs interact. This fruit, which changes the absorption of medicine in the intestine and the way it is transported in the body, can affect more than 50 medicines. For example, it reduces the effectiveness of fexofenadine, which is prescribed to treat allergies, and increases the effectiveness of atorvastatin, which is a cholesterol-lowering drug.

Milk

This Dairy products can make it harder for the body to process certain antibiotics. Milk protein called casein and minerals in it such as calcium and magnesium play a role in these effects. If you're on antibiotics, learn about foods or drinks you should avoid.

Licorice

Some people use licorice as an herbal remedy to help digestion and some others use it to flavor food. But glycyrrhizin, a chemical found in licorice, can weaken the effectiveness of a number of drugs, including cyclosporine, which is prescribed after organ transplants.

Chocolate

Dark chocolate Reduce the effect of Zolpidem Tartrate, which is prescribed to help you relax or sleep. Gives. It can also increase the potency of some stimulant drugs such as Ritalin or Methylphenidate. In addition, if you are using monoamine oxidase inhibitors to treat depression, chocolate may raise your blood pressure dangerously. reduces. Levothyroxine is a medication prescribed when you have hypothyroidism and your body cannot make enough thyroid hormone. If you use this medicine and a multivitamin, check to see if your multivitamin contains iron. Also, if you need an iron supplement, ask your doctor about how to take it.

Coffee

BingMag.com What is drug interaction and which drugs and foods should not be taken together?

This popular drink can weaken antipsychotic drugs such as lithium and clozapine, but the effects and side effects of aspirin, epinephrine, which is used to treat serious allergic reactions. and increase Albuterol, which helps to relieve breathing problems. It can also make it harder for the body to absorb and use iron.

Antihistamines

These medications help treat sneezing and runny noses caused by allergies, but some can Antihypertensive drugs are less effective and increase the heart rate. If you take medication to treat high blood pressure, talk to your doctor about other ways to control allergies.

Antiepileptic drugs

These drugs control seizures in people with epilepsy, but they can Reduce the effectiveness of birth control pills. Also, research has shown that antiepileptic drugs may increase the effect of other drugs and lead to serious side effects.

Vitamin K

If warfarin is used to prevent blood clots. you use, be careful about the amount of vitamin K you get. This vitamin can reduce the effectiveness of warfarin and put you at risk of blood clots. Broccoli, parsley and spinach are rich in vitamin K. This vitamin is also found in food supplements. Try to get the same amount of vitamin K every day to keep the warfarin blood level stable.

Ginseng

Ginseng reduces the effects of warfarin and if you use non-steroidal anti-inflammatory drugs such as ibuprofen or Naproxen and blood thinners such as heparin or aspirin increase the risk of internal bleeding. If you are taking monoamine oxidase inhibitors, ginseng may cause headaches, sleep problems, and hyperactivity. John's Wort) is used to help people with depression. This herbal medicine weakens some medicines by releasing enzymes from the liver. These drugs include cholesterol-lowering drugs such as lovastatin, erectile dysfunction drug Viagra or Sildenafil, and digoxin, which is used to treat heart disease.

Ginkgo biloba

BingMag.com What is drug interaction and which drugs and foods should not be taken together?

Some people use ginkgo biloba to treat high blood pressure, dementia, tinnitus, and other ailments, but no There is no research that proves the effectiveness of this plant. Ginkgo biloba can reduce the effect of drugs used to control seizures, including carbamazepine and valproic acid.

Factors influencing drug interactions

Personal characteristics can may play a role in the occurrence of drug interactions:

  • Genetics: Some people process drugs faster or slower than others due to their specific genetic codes, which causes a decrease or increase The effectiveness of the drugs becomes.
  • Weight: The dosage of some drugs is determined according to the person's weight.
  • Age: with As we age, body changes may affect how we react to drugs.
  • Gender: Anatomy and body hormones play a role in drug interactions. For example, men's body metabolizes Zolpidem twice as fast as women. Lifestyle: Exercise and some diets can change the effectiveness of drugs. For example, high consumption of fat has an effect on asthma medications, and exercise increases the possibility of hypoglycemia in diabetic patients by increasing the effectiveness of injected insulin. Addictive to some medications, including painkillers and anticonvulsants. Therefore, if you have been using these drugs for a long time, their dosage may need to be adjusted. You take it daily.
  • How to take medicine: Medicines are taken orally, by injection and topically. The way the drug enters the body can greatly change its effects.
  • Sequence of taking medications: Taking medications at different times can reduce the risk of adverse interactions.

Final Word

Research has shown that only 50% of medicines are taken according to the doctor's prescription. Often, people take less medication than needed or space the doses too far apart, all of which can weaken the medication's effectiveness. If you are prescribed medication, make sure you are well aware of your treatment plan and follow your doctor's instructions. Be careful with your medications. All doctors who prescribe you should be aware of all the medications, herbs and supplements you are taking. Even if you only use one drug, it is better to consult your doctor or pharmacist about its possible interactions. This recommendation applies to over-the-counter drugs and drugs prescribed by a doctor.

This article is for educational and informational purposes only. Before using the recommendations of this article, be sure to consult a specialist doctor. For more information, read BingMag Disclaimer.

Sources: webmd, healthline

Leave a Reply

Your email address will not be published. Required fields are marked *